Fmoc-D-Cyclohexyl glycine（CAS# 198543-96-3)
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Informasi Fmoc-D-Cyclohexyl glycine（CAS# 198543-96-3)
| Gunakake | Fluorene methoxycarbonyl D-cyclohexylglycine minangka perantara farmasi lan kimia umum, fluorenyl chloride (FMOC-Cl) minangka kloroformat. Iki digunakake kanggo mbentuk fluorene methoxycarbonyl (grup FMOC) dadi fluorene methoxycarbonyl carbamate FMOC carbamate, yaiku klompok pelindung amino umum. |
| Persiapan | Sintesis fluorene methoxycarbonyl D-cyclohexylglycine wis dilaporake ing literatur. Nggunakake sikloheksil bromida minangka bahan mentah, ing ngarsane natrium alkoksida, ngalami reaksi alkilasi karo dietil malonate, lan banjur hidrolisis, acidifies, lan decarboxylates kanggo njupuk asam cyclohexyl asetat; sing terakhir banjur dibrominasi lan ammonolisis DL-Cyclohexylglycine; pungkasane, reaksi asilasi dumadi ing ngarsane fluorene methoxycarbonyl chloride kanggo entuk fluorene methoxycarbonyl D-cyclohexylglycine [1]. Rute reaksi sintesis kaya ing ngisor iki: |
Sadurunge: AC-TYR-NH2（CAS# 1948-71-6) Sabanjure: 2-Amino-4-bromobenzoic acid（CAS# 20776-50-5)
